Incidence and clinical impact of inherited thrombophilia in second trimester pregnancies with abnormal uterine Doppler

Objective: Abnormal uterine perfusion in second trimester is one of the main prognostic indicators for complications in pregnancy such as preeclampsia and IUGR. As inherited thrombophilia is also associated with an increased risk for these complications, this study was to evaluate if these two parameters show any association regarding perinatal outcome and whether thrombophilia can be used as a further criterion for risk assessment. Methods: 137 singleton pregnancies between week 18–26 were included in this retrospective study. All women were characterized by an abnormal uterine perfusion (mean pulsatility index…