Assessment of tumor response to antiangiogenic chemotherapy for hepatic breast cancer metastases: Imaging of the malignant neoangiogenesis with perfusion ct vs. contrast-enhanced…

Objectives: Malignant angiogenesis affects tumor growth, local expansion and metastasis. Antiangiogenic chemotherapies act to reduce tumoral cell growth acting as angiogenesis inhibitor for endothelial cells. Objective tumor response is a common endpoint to evaluate the efficacy of anticancer agents. World Health Organization (WHO) or Response Evaluation Criteria in Solid Tumors Group (RECIST) criteria are not appropriate for the evaluation of targeted therapy because tumoral hypoxia is independent from tumor volume. The purpose of this study was to evaluate whether CEUS could be used to evaluate tumor response…