Time intensity curves – reliability and possible sources of errors

Aims: Time intensity curves (TIC) can be used to analyse focal and diffuse diseases of the liver, the kidney, the breast and other organs. In contrast to ordinary contrast investigations quantitative parameters like time to peak (TTP), mean transit time (MTT), area under the curve (AUC), peak intensity (PI) and others can be acquired which suggests objectivity. So it is necessary to analyse features that possibly affect the reliability of this method. Methods: Analysis of the literature and 30 cases of liver, kidney, bowel and pancreas lesions to determine the effect of e.g. the design, the size and the position…