Factors present in peritoneal fluid of endometriosis patients inhibit drug-induced apoptosis and induce migration of endometrial and endometriotic cells

Several studies have shown evidences of changes in peritoneal fluid composition in women with endometriosis. An altered function of peritoneal immune cells and higher levels of soluble substances such as cytokines, growth factors and prostaglandins are found in women with endometriosis compared to those without the disease. These variations in the composition of the peritoneal fluid are likely to play a crucial role in the formation and development of endometriosis. The aim of this study was to evaluate peritoneal fluid of patients with endometriosis with regard to its influence on survival and migration of endo…