CareLit Fachartikel
Differential expression of adipokines due to hypoxia in brown and white adipocytes
A Wree, A Mayer, S Westphal, R Schick, J Klein, G Gerken, AE Canbay, P Vaupel · Zeitschrift für Gastroenterologie · 2010 · Heft 01
Dokument
1168059
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Jahr
2010
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Zusammenfassung
Background: Adipose tissue, consisting of white and brown adipocytes, comprises an important endocrine regulator, secreting hormones specified as adipokines. While recent studies demonstrated that adipose tissue responds to hypoxia, the different roles of regulation in brown and white adipocytes are still unclear. In this study the effect of hypoxia on murine brown and white adipocyte cell lines was analyzed. Methods: In cultured adipocytes hypoxia was induced chemically with desferoxamine and cobaldchlorid or physically in an atmosphere of 1% oxygen. Vitality and differentiation was tested by oil-red-staining.…
Schlagworte
Adipocytes
Adipokines
Angiotensinogen
Adiponectin
Atmosphere
Zeitschrift für Gastroenterologie
