Non-invasive assessment of liver fibrosis in HIV infected adults with and without HCV / HBV co-infection and exposure to dideoxynucleosides
A Kau, J Vermehren, A Müller, A Carlebach, T Lutz, P Gute, G Knecht, L Locher, E Herrmann, M Friedrich-Rust, N Forestier, C Sarrazin, S Zeuzem, WP Hofmann · Zeitschrift für Gastroenterologie · 2010 · Heft 01
Bibliografische Angaben
Zusammenfassung
Aims: Liver disease is a common complication in individuals with HIV infection. Recently, exposure to antiretroviral agents such as dideoxynucleosides (i.e. stavudine, didanosine, and zalcitabine) has been recognized as a potential cause of liver injury which over time may lead to significant liver fibrosis. Transient elastography allows for non-invasive assessment of liver fibrosis and may be helpful to characterize dideoxynucleoside-related hepatic side effects. Methods: Transient elastography (FibroScan, Echosens, France) was performed in 190 consecutive individuals (151 men, mean age 47±9 years) with HIV mon…
