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Improved diagnostic accuracy of transient elastography for cirrhosis using histology plus clinics as gold standard

S Mueller, G Millonig, F Stickel, T Longerich, P Schirmacher, HK Seitz · Zeitschrift für Gastroenterologie · 2010 · Heft 01

Dokument
1168069
CareLit-ID
Jahr
2010
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Gastroenterologie
Autor:innen
S Mueller, G Millonig, F Stickel, T Longerich, P Schirmacher, HK Seitz
Ausgabe
Heft 01 / 2010
Seiten
–
Erschienen: 2010-01-12 00:00:00
ISSN
0044-2771

Zusammenfassung

Aims: Measurement of liver stiffness (LS) by transient elastography (Fibroscan, FS) is a novel noninvasive approach to assess liver fibrosis with a high diagnostic accuracy. However, accuracy may be even higher since histology served as gold standard in all previous LS studies although its sample error may reach up to 30%. Consequently, we here determined the AUROC for FS to detect liver cirrhosis using a combination of histology and definite clinical signs of cirrhosis as obtained by ultrasound or gastroscopy in patients with alcoholic liver disease (ALD). Method: LS was measured in 90 patients with histologica…

Schlagworte

Fibroscan alcoholic liver disease cirrhosis liver biopsy liver stiffness Diagnosis Biopsy Zeitschrift für Gastroenterologie