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Y-box protein–1/p18 fragment identifies malignancies in patients with chronic liver disease

F Tacke, N Kanig, E Yagmur, A En-Nia, CS Eberhardt, C Trautwein, PR Mertens · Zeitschrift für Gastroenterologie · 2008 · Heft 01

Dokument
1168233
CareLit-ID
Jahr
2008
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Gastroenterologie
Autor:innen
F Tacke, N Kanig, E Yagmur, A En-Nia, CS Eberhardt, C Trautwein, PR Mertens
Ausgabe
Heft 01 / 2008
Seiten
–
Erschienen: 2008-01-23 00:00:00
ISSN
0044-2771

Zusammenfassung

Background & aims: Immunohistochemical detection of cold shock proteins is predictive for deleterious outcome in various malignant diseases. The active secretion of a family member, denoted Y-box (YB) protein–1, was recently discovered by our group. As effective screening tools for malignant diseases are warranted for high risk populations such as patients with liver cirrhosis considered for potential transplantation, we tested the clinical and diagnostic value of YB–1 protein fragment p18 (YB–1/p18) detection in blood for malignant and liver diseases in different cohorts of patients. Patients & methods: We used…

Schlagworte

HCC Krebs Lebertumor Leberzirrhose YB-1 Transplantation Tumor Blood Alpha-Fetoprotein Zeitschrift für Gastroenterologie