Health-related Quality of Life decreases with disease severity in German HSP Patients
S Klimpe, R Schüle-Freyer, J Kassubek, T Klopstock, Z Kohl, S Klebe, S Otto, S Döhlinger, M Dieterich, L Schöls · Klinische Neurophysiologie · 2008 · Heft 04
Bibliografische Angaben
Zusammenfassung
Background: The Hereditary Spastic Paraplegias (HSP) comprise of a clinically and genetically heterogeneous group of neurodegenerative disorders characterised by a slowly progressive spastic gait disorder. Clinically, „pure“ and „complicated“ forms are distinguished. The impact of HSP on quality of life is not known so far. Therefore, we assessed the health-related quality of life with the Short-Form 36 (SF-36) quality of life questionnaire in a sample of HSP patients of the GeNeMove network project. Patients and Methods: 123 patients with HSP (47.2% women, mean age 47.4; 16–80 years) participating in the GeNeMo…
