Differential diagnostic value of eye movement recording in PSP-Parkinsonism, Richardson's Syndrome, and Idiopathic Parkinson's Disease

Objectives: Vertical gaze palsy is a highly relevant clinical sign in Parkinsonian syndromes. As the eponymous feature it is one of the core features in the diagnosis of progressive supranuclear palsy (PSP). Recent studies have suggested a further differentiation of PSP in Richardson's Syndrome (RS) and PSP-Parkinsonism (PSP-P). The aim of this study was to search for oculomotor abnormalities in the PSP-P subset out of a sample of PSP patients and to compare these findings with those of RS patients, patients with Idiopathic Parkinson's disease (IPD) and a control group. Materials and Methods: Twelve cases of RS,…