Long-term treatment with atorvastatin improves dyslipidemia and vascular function in patients with primary biliary cirrhosis
T Stojakovic, C Putz-Bankuti, H Scharnagl, M Wagner, H Sourij, W März, TC Wascher, M Trauner · Zeitschrift für Gastroenterologie · 2008 · Heft 06
Bibliografische Angaben
Zusammenfassung
Background and aims: Primary biliary cirrhosis (PBC) is frequently associated with hypercholesterolemia and possibly an increased cardiovascular morbidity and mortality. Statins have the potential to lower serum cholesterol levels and may thus reduce the cardiovascular risk in PBC patients. The aim of our study was to prospectively examine the safety and efficacy of long-term treatment with low-dose atorvastatin on dyslipidemia, cardiovascular risk factors and vascular function in patients with PBC. Methods: Nineteen patients with early stage PBC (biopsy proven and AMA positive) and low-density lipoprotein chole…
