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Neural substrates of the pessimistic bias in major depressive patients compared to healthy subjects
T Kaffenberger, U Herwig, A Brühl, C Schell · Klinische Neurophysiologie · 2010 · Heft 03
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1168974
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Jahr
2010
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Zusammenfassung
Introduction: Pessimism, to expect the worse outcome in case of uncertainty, is a main cognitive feature of major depression. Depressive patients are characterized by a negative attitude towards themselves, the world and the future as described in Beck's cognitive triad [1]. Our aim was to analyze the neural correlates of these features of cognitive processing in depression concerning the pessimistic attitude. We hypothesized reduced emotional arousal and thus reduced interoceptive activation in patients versus healthy subjects watching a negative picture after an uncertain announcement, indicating either a posi…
Schlagworte
Depression
After
Depressive Disorder
Amygdala
Bias
Klinische Neurophysiologie
