Establishment and molecular characterization of six primary pancreatic cancer cell lines

Pancreatic carcinoma ranks among the most deadly carcinomas. Basic research in this field is dependent on the availability of pancreatic cancer cell lines. Although several established cell lines are available it is necessary to isolate new primary cell lines for molecular analysis because of the tumor-heterotypic expression of many target genes in the individual patients and the genetic drift of established cell lines. A further benefit is the availability of a nearly endless source of tumor cells, additional to the samples of existing tissue banks. Because of this, the Department of Visceral-, Thoracic and Vas…