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Cholesterol in mild cognitive impairment and Alzheimer's disease in a prospective population based study in Germany

J Schröder, C Sattler, P Schönknecht, P Toro · Das Gesundheitswesen · 2010 · Heft 09

Dokument
1169685
CareLit-ID
Jahr
2010
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Das Gesundheitswesen
Autor:innen
J Schröder, C Sattler, P Schönknecht, P Toro
Ausgabe
Heft 09 / 2010
Seiten
–
Erschienen: 2010-09-02 00:00:00
ISSN
0941-3790
DOI
10.1055/s-0030-1266589

Zusammenfassung

Introduction: Animal research and epidemiological studies identified cholesterol as a risk factor for mild cognitive impairment (MCI) and Alzheimer's disease (AD). We therefore investigated the potential impact of plasma total cholesterol (TC) on the development of MCI and AD in a longitudinal study of a representative birth cohort born between 1930 and 1932. Methods: 500 participants of the Interdisciplinary Longitudinal Study on Adult Development and Aging (ILSE) were examined in 1993–1996 (t1), 1997–2000 (t2) and 2005–2008 (t3). Results: Prevalence of MCI increased from 13% to 23% and 29% over time; in additi…

Schlagworte

ApoE4 Cholesterol Population Diagnosis Germany Allele Aging Das Gesundheitswesen