CareLit Fachartikel
Impact of biochemical markers NSE and S100beta for detection and monitoring of subclinical and manifest hepatic encephalopathy
F Gundling, H Strebel, T Schmidt, W Schepp, C Pehl · Zeitschrift für Gastroenterologie · 2010 · Heft 09
Dokument
1169750
CareLit-ID
Jahr
2010
Publikation
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Metadaten
DOI
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zitierfähig
Bibliografische Angaben
Zusammenfassung
Background and Aims: Proton magnetic resonance spectroscopy (1H-MRS) studies of the human brain gave an indication of the presence of low grade cerebral edema in patients with cirrhosis (1). Based on this observation it was hypothesized that hepatic encephalopathy (HE) reflects the clinical manifestation of a low grade cerebral edema, which may worsen under the influence of precipitating factors and thereby trigger cell hydration-dependent alterations of astrocyte function and volume homeostasis. Such alterations may affect glial-neuronal communication, whose disturbance is considered to be relevant to the patho…
Schlagworte
Blood
1H-MRS
After
Basal Ganglia
Observation
Diagnosis
Calcium
Affect
Zeitschrift für Gastroenterologie
