Epithelial to mesenchymal transition in liver regeneration
A Widera, G Campos, B Begher-Tibbe, G Günther, C Garcia-Perez, R Stöber, JG Hengstler, P Godoy · Zeitschrift für Gastroenterologie · 2011 · Heft 01
Bibliografische Angaben
Zusammenfassung
The process of liver regeneration is unique in regard to other organs. It presents the ability to recover up to 70% of the organ mass in a very short time frame of a few days, while also preserving quite efficiently the fine and unique architecture of the multicellular components (e.g. hepatocytes, sinusoiodal cells, etc) which is fundamental for its functions. Our investigations have shown, based on computer models generated using time series of confocal images from regenerating liver after CCl4 induced damage that a novel aspect which is hepatocytes movement in order to align within sinusoids is fundamental fo…
