Pediatric Acute Hepatic Failure: Longer Duration Of Pre-Tertiary Care Is Associated With Increased Risk of Death Staging

Aims: In pediatric acute liver failure (PALF), rapid transfer to a liver transplantation center (LTC) is advocated for optimal outcome. Aim: To analyze the duration of pre-tertiary care (DPTC) before transfer to a LTC and its effect on outcome predictors and on a risk of death staging system. Methods: Charts of 47 PALF patients were retrospectively reviewed and according to DPTC divided into two cohorts: cohort 1 (n=24) with DPTC 7 days 12 vs. 2. ALAT levels at LTC admission 1144 vs. 2545 U/l (median). The LIU score in cohort 2 was significantly higher than in cohort 1: 246 vs. 156 units (median, p