Outcome of cyclosporine rescue therapy or surgery in patients with steroid-refractory ulcerative colitis: both improve the quality of life despite of the frequent complications

Introduction: Patients with ulcerative colitis (UC) usually can not accept the need for colectomy; however rescue therapies may cause severe side-effects. The aim of our study was to compare the outcome and the changes of quality of life in patients with steroid-refractory UC before and after cyclosporine rescue therapy or colectomy. Patients and Methods: Data of 90 steroid-refractory UC patients were analyzed retrospectively, of which 46 patients underwent colectomy and 44 patients responded to cyclosporine therapy. Every patient assessed their quality of life at the time of the diagnosis of UC, three month bef…