Quantification of the 3-Dimensional Glomeruli Capillary System in Adult Pigs using Micro- and Nano-CT Imaging
AC Langheinrich, E Schneck, F Scheiter, M Kampschulte · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2011 · Heft 04
Bibliografische Angaben
Zusammenfassung
Ziele: To evaluate the feasibility for analysis of the kidney glomeruli capillary unit in adult pics using micro- and nano-CT imaging. Methode: Kidneys were harvested from five healthy hybrid pics (6 mo of age; weight 120kg) at a local slaughterhouse and infused with a mixture of BaSO4 and gelatine. Kidney samples (6-mm diameter, 10mm height, n=20) were punched out, harvested and scanned with micro-CT (12µm cubic voxels) and nano-CT (450nm cubic voxels). Diameter and cross-sectional area (µm2) of glomeruli were measured using micro-CT, nano-CT and histology. Moreover, the capillary vessel volume (mm3) within sin…