CareLit Fachartikel

Expression pattern of GPR30 in endometriosis

EP Samartzis, N Samartzis, A Noske, A Fedier, R Caduff, D Fink, P Imesch · Geburtshilfe und Frauenheilkunde · 2011 · Heft 06

Dokument
1170442
CareLit-ID
Jahr
2011
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Geburtshilfe und Frauenheilkunde
Autor:innen
EP Samartzis, N Samartzis, A Noske, A Fedier, R Caduff, D Fink, P Imesch
Ausgabe
Heft 06 / 2011
Seiten
–
Erschienen: 2011-06-06 00:00:00
ISSN
0016-5751
DOI
10.1055/s-0031-1280499

Zusammenfassung

Introduction: G-protein coupled receptor 30 (GPR30) is a seven-transmembrane receptor suggested to be part of non-genomic estrogen responses that can, in contrast to the classic or genomic mode of ER action, occur rapidly within minutes. GPR30 mediated estrogen action is involved in multiple physiological processes, as well as pathological processes, as for example the proliferative effects of estrogen and tamoxifen in endometrial cancer cells. Since Estrogen action plays a key role in endometriosis and is partly mediated by GPR30 in a various number of physiological and pathological processes, the investigation…

Schlagworte

Gpr30 Endometriosis Estrogen Endometrial Expression Action Processes Cells Could Tissue Endometriotic Receptor Geburtshilfe und Frauenheilkunde