CareLit Fachartikel
Xanthohumol improves glucose tolerance and inhibits hepatic steatosis, inflammation and fibrogenesis in a murine model of non-alcoholic steatohepatitis
C Dorn, C Hellerbrand · Zeitschrift für Gastroenterologie · 2012 · Heft 01
Dokument
1170838
CareLit-ID
Jahr
2012
Publikation
PDF
nein
Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Xanthohumol, the principal prenylated flavonoid of the female inflorescences of the hop plant, has been most extensively studied as cancer chemopreventive agent. In addition, anti-inflammatory properties have been demonstrated in various organs including the liver. Nonalcoholic fatty liver disease (NAFLD) is considered as hepatic manifestation of the metabolic syndrome, and in a subset of cases hepatic steatosis progresses to steatohepatitis (NASH), which may further advance with significant fibrosis. The aim of this study was to investigate the effect of xanthohumol in a dietary murine model of obesity, hypergl…
Schlagworte
Blood Glucose
Obesity
Blood
Affect
Diet
Zeitschrift für Gastroenterologie
