Chronic hepatitis E in heart transplant recipients
S Pischke, P Stiefel, B Bremer, PV Suneetha, B Franz, A Heim, T Ganzenmueller, R Raupach, A Haverich, C Bara, MP Manns, H Wedemeyer · Zeitschrift für Gastroenterologie · 2012 · Heft 01
Bibliografische Angaben
Zusammenfassung
Chronic courses of infections with the hepatitis E virus (HEV) have been described in patients after liver and kidney transplantation. We here aimed to study the role of HEV infections in heart transplant recipients. Methods: In a prospective approach, 274 heart transplant recipients were tested for serological and virological markers of HEV infection. In addition, 137 control patients undergoing cardiac surgery (bypass, cardiac valve, aneurysmata) were studied cross-sectionally. 537 healthy subjects served as controls. All patients were tested for HEV RNA (in-house-PCR) and anti-HEV-IgG (Diasorin/ Abbott ELISA)…