CareLit Fachartikel
Vitamin D and depression in chronic liver disease
CS Stokes, C Baus, M Riemenschneider, F Lammert · Zeitschrift für Gastroenterologie · 2012 · Heft 01
Dokument
1170851
CareLit-ID
Jahr
2012
Publikation
PDF
nein
Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Aims: Patients with chronic liver disease (CLD) frequently exhibit vitamin D deficiency1. Vitamin D is purported to be implicated in depression, which is co-morbid with CLD. Serum 25-hydroxyvitamin D levels often correlate inversely with depression2, and vitamin D receptors (VDR) are confirmed to be involved in depression pathophysiology in the brain3. Behavioural impairment and increased anxiety are demonstrated in VDR knockout mice compared to controls4. Human studies show VDR gene variants to influence depression5. This study investigates the potential of vitamin D supplementation in ameliorating depressive s…
Schlagworte
25-hydroxyvitamin D
vitamin D receptor
Depression
Association
Anxiety
Aging
Zeitschrift für Gastroenterologie
