CareLit Fachartikel
Phylogenetic Characterization of HEV Isolates Derived from Acute Hepatitis E Cases in Germany 2010/2011
JJ Wenzel, M Faber, B Huber, K Stark, W Jilg · Zeitschrift für Gastroenterologie · 2012 · Heft 01
Dokument
1170858
CareLit-ID
Jahr
2012
Publikation
PDF
nein
Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Introduction: Hepatitis E virus (HEV) has been identified as an emerging cause of infectious hepatitis over the last years in developed countries. In contrast to travel associated hepatitis E (HEV genotype 1), autochthonous cases in Europe are associated with HEV genotype 3 isolates. However, no comprehensive data on HEV genotype spectrum and distribution are available for Germany. Methods: In 2010 and 2011 we received 50 HEV isolates from acute hepatits E cases in Germany. Samples were analyzed by quantitative RT-qPCR and conventional nested PCR prior to sequencing (variable regions in ORF1 and ORF2). Rooted ma…
Schlagworte
Hepatitis E
Phylogenetic Analysis
Germany
Hepatitis
Database
Trees
Zeitschrift für Gastroenterologie
