Comparison of Assessment of Myocardial Perfusion by CT-based Dynamic Myocardial Perfusion Imaging and Single-Phase High-Pitch Acquisitions in a Porcine Animal Model with Various D…

Purpose: To determine the correlation between myocardial blood-flow (MBF) derived from CT-based dynamic myocardial perfusion imaging and enhancement on single-phase using high-pitch scans (SPE) in a porcine animal model with variable coronary artery stenosis. Methods and Materials: Country pigs underwent stent placement to the proximal left anterior descending artery, in which a balloon catheter was inflated to simulate luminal narrowing (50% and 75% diameter stenosis, verified by flow-wire measurement). All animals underwent adenosine-mediated dynamic stress- and rest-CT-imaging using a Dual-Source CT-system. I…