Voxel based morphometry showing acute alteration in a visual paradigm

Aims: Previous studies used voxel based morphometry (VBM) for imaging long term alteration within the gray matter of the brain. Increased and decreased densities were reported after special conditions such as learning to juggle or pain application and were interpreted as signs of cerebral neuroplasticity over time. Acute changes of cerebral activation have been only studied by functional imaging such as functional magnetic resonance imaging (fMRI) and positron emission tomography (PET). Objectives: To investigate whether VBM can also detect acute changes induced by a simple checkerboard paradigm. Methods: Twenty…