CareLit Fachartikel
A Resting-State fMRI Analysis to Reveal Changes in Functional Connectivity Patterns of the DLPFC in Patients with Parkinson’s Disease
N Schmidt, O Granert, S Wolff, T van Eimeren, K Witt · Klinische Neurophysiologie · 2012 · Heft 03
Dokument
1171037
CareLit-ID
Jahr
2012
Publikation
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Metadaten
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Zusammenfassung
Introduction: The characteristic motor symptoms in Parkinson’s disease (PD) are often accompanied by cognitive, emotional and motivational deficits, which are modulated by dysfunctions of the fronto-striatal loops. The dorsolateral prefrontal cortex (DLPFC) is known to be involved in executive functioning. While activations of the DLPFC during executive tasks are well described, the impact of resting state functional connectivity (FC) of the DLPFC on cognitive changes remains to be specified. In a first step, changes in FC of the DLPFC in PD patients are determined. Methods: We examined 53 PD patients and 16 age…
Schlagworte
Dlpfc
Group
Patients
Statistical
Correlation
Coefficients
Differences
Changes
Functional
Connectivity
Cognitive
Control
Klinische Neurophysiologie
