Assessment of residual bulky tumor using FDG-PET in patients with advanced stages after completion of chemotherapy. Final report of the GHSG HD15 trial
C Kobe, A Engert, J Markova, H Haverkamp, HT Eich, RP Müller, A Holstein, D Kahraman, M Dietlein, P Borchmann, V Diehl · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2012 · Heft 04
Bibliografische Angaben
Zusammenfassung
Ziele: The role of additional radiotherapy after chemotherapy for advanced-stage Hodgkin lymphoma (HL) is unclear. The German Hodgkin Study Group (GHSG) thus performed the HD15 trial in which advanced-stage HL patients having residual disease after 6–8 cycles of BEACOPP were evaluated by 18F-FDG-PET following chemotherapy. Methode: Entry criteria for the PET question in HD15 were partial remission after the end of chemotherapy with at least one involved nodal site measuring more than 2.5cm in diameter by CT. A total of 2182 patients with de novo HL were included in HD15 of whom 740 wee qualified for the PET ques…