Potential MRNA biomarkers of colorectal dysplasia-carcinoma transition based on gene expression analyses
A Kalmár, O Galamb, S Spisák, K Tóth, B Wichmann, F Sipos, G Valcz, K Leiszter, VÁ Patai, A Schöller, I Fűri, Z Nagy, B Barták, B Molnár, Z Tulassay · Zeitschrift für Gastroenterologie · 2012 · Heft 05
Bibliografische Angaben
Zusammenfassung
Introduction: Though histopathology is still the gold standard for differentiating stages of colorectal disease progression, the early molecular detection of the colorectal dysplasia-carcinoma transition may enhance the strength of diagnosis from colonic biopsies. Using high-throughput microarray-based biomarker screening low cost diagnostic array real-time PCR panels may be developed. Aims: Our aim was to determine molecular markers for enhancing the differentiation of high-grade dysplasia from colorectal carcinoma (CRC) and to analyze the applicability of FFPE tissue samples. Material and Methods: HGU133Plus2.…
