Identification of circulating microrna pattern alteration during the tumor development using C38/C57BL/6 mouse tumor model
Z Nagy, B Barták, S Spisák, B Wichmann, A Kalmár, VÁ Patai, A Schöller, K Tóth, K Leiszter, B Molnár, Z Tulassay · Zeitschrift für Gastroenterologie · 2012 · Heft 05
Bibliografische Angaben
Zusammenfassung
Introduction: Analysis of miRNA plays important roles in fields of functional and biomarker discovery in recent years. It has been shown that cell-free DNA and RNA can be detected from serum and other body fluids. Expression profiles of miRNAs altered along tumor formation, furthermore these miRNAs may spread into tumor microenviroment. The mechanisms of these processes have not been clearified yet. Aims: Our primary aim was to analyse the alteration of the circulating miRNA profile in C38/C57BL/6 mouse tumor model. Our further aim was to identify non-tumor originated miRNA from plasma which may be originated fr…
