Low Vitamin D serum levels are associated with liver fibrosis and impaired virologic response to chronic hepatitis C therapy with Pegifn+RBV in HIV/HCV coinfected patients
M Mandorfer, T Reiberger, BA Payer, A Ferlitsch, F Breitenecker, MC Aichelburg, B Obermayer-Pietsch, A Rieger, M Trauner, M Peck-Radosavljevic · Zeitschrift für Gastroenterologie · 2012 · Heft 05
Bibliografische Angaben
Zusammenfassung
Aims: Low 25-hydroxyvitamin D (25(OH)D) levels are commonly found in HIV/HCV coinfected patients and are associated with liver fibrosis. However, in contrast to findings in HCV monoinfected patients, no association between 25(OH)D and virologic response to pegylated interferon α-2a/2b plus ribavirin (PEGIFN+RBV) has yet been reported. Methods: Epidemiological characteristics, HIV and HCV infection parameters and liver biopsies were assessed in 93 HIV/HCV coinfected patients. Data on virologic response was available in 65 patients who received chronic hepatitis C (CHC) therapy with PEGIFN+RBV. According to their…
