CareLit Fachartikel
Coffee interferes with proliferation and induces apoptosis in human cancer cell lines
SR Pérez Rosal, AD Keller, G Tiegs, G Sass · Zeitschrift für Gastroenterologie · 2013 · Heft 01
Dokument
1172293
CareLit-ID
Jahr
2013
Publikation
PDF
nein
Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Background and Aims: Numerous cohort studies revealed that coffee consumption is inversely correlated with the risk to develop cancer. Detailed in vitro studies are missing and up to now there is no mechanism defined how coffee might achieve anti-cancer activity. We investigated effects of regular and decaffeinated coffee or caffeine on viability of human breast- pancreatic- and hepatic cancer cell lines. Additionally, effects on primary mouse hepatocytes and mouse hepatoma cells were investigated. Methods: Human breast cancer (MDA-MB; MCF7), pancreatic cancer (YAPC; PANC89) and hepatoma (HepG2; Hep3B) cell line…
Schlagworte
Caffeine
Apoptosis
Tumor
Caspase 3
Breast
Beta-Catenin
beta Catenin
Observation
Zeitschrift für Gastroenterologie
