Serum cytokines and HBsAg decline in patients with acute Hepatitis B Virus (HBV) infection
AA Markova, J Jaroszewicz, M Rogalska-Taranta, C Falk, SB Wiegand, K Port, B Maasoumy, B Calle Serrano, R Flisiak, MP Manns, H Wedemeyer, M Cornberg · Zeitschrift für Gastroenterologie · 2013 · Heft 01
Bibliografische Angaben
Zusammenfassung
Background: HBsAg loss and seroconversion is the ultimate goal of therapy for chronic HBV infection. However, HBsAg loss is a rare event even with antiviral therapy. In contrast, the majority of adults with acute HBV infection achieve HBsAg loss. The analysis of the natural course of acute HBV infection may help to define correlates of immune control of HBV. The aim of this study was to analyse serum cytokines and their association with dynamics of HBsAg clearance during acute HBV infection. Methods: A panel of 15 serum cytokines and chemokines was assessed in 15 patients with symptomatic acute HBV infection who…
