Bioactivity-guided isolation of compounds with xanthine oxidase inhibitory activity from Onopordum acanthium
I Lajter, B Csupor-Löffler, O Orbán-Gyapai, N Jedliszki, P Forgo, A Vasas, J Hohmann · Zeitschrift für Phytotherapie · 2013 · Heft 03
Bibliografische Angaben
Zusammenfassung
Onopordum acanthium L. is naturalized in various parts of the world, including Hungary. O. acanthium has been used traditionally for its antibacterial, hemostatic, and hypotensive properties. Moreover, the juice has been considered to be effective against cancerous ulcers, carcinoma of the face and other cancers in traditional medicine [1]. Previous studies revealed the presence of lupeol, amyrin, taraxasterol and its acetate, onopordopicrin and arctiopicrin [2, 3]. Xanthine oxidase (XO) inhibitory screening of Asteraceae species demonstrated high activity of methanol extract of O. acanthium. XO is a late enzyme…