Comparison of ADC Diffusion Maps and CBV Perfusion Maps in Patients with Newly Diagnosed Glioblastoma: Establishing Order in Heterogeneity
A Radbruch, K Lutz, M Graf, R Floca, HP Schlemmer, s Heiland, M Bendszus · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2013 · Heft 04
Bibliografische Angaben
Zusammenfassung
Ziele: Diffusion MRI (DWI) and dynamic-susceptibility-contrast weighted perfusion MRI (DSC) have been proposed to distinguish areas of different malignancy in glioblastoma. The aim of this study was to evaluate, whether or not areas of minimum ADC and maximum CBV do overlap. Methode: DWI, DSC and contrast-enhanced T1-weighted Imaging (ce-T1) was performed in 20 patients with newly diagnosed glioblastoma on a 3 Tesla MR. ADC and CBV maps were acquired, coregistered on ce-T1, and threasholds of CBV and ADC were visualized using a specially developed software based on MeVisLab. A ROI was manually delineated with ap…