Evaluation of bone turn over markers in patients with chronic hepatitis B infection and under Tenofovit treatment

Aim: Bone health depends on renal function and active bone metabolism in chronic hepatitis B (CHB). Differences of serum levels of bone turnover markers were studied in patients with active and inactive CHB. Markers were compared at baseline and after 3 months of treatment with tenofovir (TDF). Materials and methods: Twenty-five patients with active CHB and indication for antiviral treatment with TDF according to current guidelines for management of CHB and 34 patients with inactive CHB were investigated. Serum levels of osteocalcin (OC), fibroblast growth factor 23 and C-terminal telopeptide of type I collagen…