Metagenome analysis of plasma derived CFDNA in healthy patients and colon diseases
B Barták, S Spisák, N Solymosi, P Ittzés, A Bodor, D Kondor, G Vattay, Z Nagy, A Kalmár, A Schöller, F Sipos, O Galamb, Z Tulassay, I Csabai, B Molnár · Zeitschrift für Gastroenterologie · 2013 · Heft 05
Bibliografische Angaben
Zusammenfassung
Introduction: There are many theory of the cell free DNA (cfDNA) origin such as apoptosis, necrosis and active secretion; however the exact nucleotide composition is unknown. We are constantly exposed to foreign DNA from various sources like benign or malicious microbes in and on our body, pollens in the inhaled air and as the largest amount with the daily food supply. Here we report a new possible mechanism, which can be contribute the quantity and quality of the cfDNA. Aims: Our aims were to determine the DNA content of cfDNA by NGS sequencing technology and identify differences among four clinical groups and…
