Early vs. late intervention in twin reversed arterial perfusion (TRAP) sequence

Purpose: To compare two different management approaches in prenatally diagnosed TRAP-sequence. Material and methods: Retrospective analysis of all cases with TRAP sequence diagnosed in one centre over a period of 10 years. Prior to 2009 all cases were managed expectantly until 19 weeks gestation. Thereafter patients could either choose radiofrequency ablation (RFA) or expectant management. After 2009 all patients were offered interstitial laser from the first trimester onward or expectant management. Results: In the study period 46 cases of TRAP-sequence were diagnosed. Three pregnancies were terminated leaving…