Imaging the vestibular system after acute unilateral midbrain infarction – A combined lesion-behaviour mapping and FDG-PET study

Introduction: The aim of this study was twofold, to determine 1) relevant vestibular midbrain structures by voxelwise lesion-behavior mapping (VLBM), and 2) whether PET activation pattern in acute midbrain lesions affecting ascending vestibular tracts differs from that found in patients with acute medullary [1] or peripheral vestibular lesions [2]. Methods: Subjective visual vertical (SVV) was tested in 17 patients with acute unilateral mesothalamic strokes. On the basis of evident SVV tilt (n = 8), patients were devided in two groups before VLBM. Patients with SVV tilt (n = 8) underwent resting state FDG-PET tw…