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Combined analysis of perinatal and infant risk factors for type 1 diabetes

R Chmiel, C Winkler, A Beyerlein, M Köhler, A Knopff, C Matzke, M Scholz, AG Ziegler · Diabetologie und Stoffwechsel · 2014 · Heft 05

Dokument
1174171
CareLit-ID
Jahr
2014
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Diabetologie und Stoffwechsel
Autor:innen
R Chmiel, C Winkler, A Beyerlein, M Köhler, A Knopff, C Matzke, M Scholz, AG Ziegler
Ausgabe
Heft 05 / 2014
Seiten
–
Erschienen: 2014-05-06 00:00:00
ISSN
1861-9002
DOI
10.1055/s-0034-1375059

Zusammenfassung

Aims/hypothesis: The aim of the present study was to determine if risk of developing early islet autoimmunity and/or type 1 diabetes can be stratified by combined analysis of perinatal and infant environmental factors. Methods: We prospectively followed 2441 children with a family history of type 1 diabetes from the German birth cohort studies BABYDIAB and BABYDIET for the development of islet autoantibodies and diabetes. Median follow-up-time to last sample was 10.2 years. Data on perinatal and infant exposures was collected by prospective questionnaires and family interview (mother smoking during pregnancy, ma…

Schlagworte

Autoimmunity Maternal Age Autoantibodies Diet Diabetologie und Stoffwechsel