Effects of the menstrual cycle on the endothelial glycocalyx (EGX) and leucocyte function
N Rogenhofer, N Eckert, I Götzfried, T Nguyen, J Pagel, T Kammerer, S Hilferink, F Klug, K Hofmann-Kiefer, A Chouker, M Rehm, CJ Thaler · Geburtshilfe und Frauenheilkunde · 2014 · Heft 09
Bibliografische Angaben
Zusammenfassung
Introduction: The endothelial glycocalyx is pivotal for a healthy vascular barrier. Recent data showed an increase of glycocalyx components in the circulating blood during normal pregnancy and HELLP-syndrome. We investigated, if there is a change in the integrity of the glycocalyx during normal menstrual cycle, which could explain premenstrual edemas. Materials and methods: This study includes 21 healthy females having a normal menstrual cycle. 10 males and 6 postmenopausal volunteers served as controls. In the follicular phase (cycle day 3 – 4), ovulation (urinary LH-peak), and luteal phase (8 days after urinar…