Use of beta-blockers is associated with improved 30 day survival in patients with spontaneous bacterial peritonitis
P Lutz, HD Nischalke, B Krämer, B Langhans, S Schlabe, J Nattermann, A Hoerauf, CP Strassburg, U Spengler · Zeitschrift für Gastroenterologie · 2015 · Heft 01
Bibliografische Angaben
Zusammenfassung
Introduction: Use of beta-blockers after spontaneous bacterial peritonitis (SBP) leads to increased long-term mortality. However, the effect on survival of the infection is unclear. In a murine peritonitis model, inhibition of the neuroadrenergic system even increased survival. Thus, we studied the role of beta-blockers for short-term survival in patients with SBP. Methods: We determined transplant-free 30-day survival in cirrhotic patients who developed SBP between March 2012 and April 2014 in our department. Interleukin 8 (IL-8) was measured in in ascites supernatant by ELISA. Ascites cells were stimulated in…
