Kinetic of Hepatitis B core-related antigen (HBcrAg) levels in chronic hepatitis B during NUC therapy
B Maasoumy, J Jaroszewicz, K Deterding, P Lehmann, B Bremer, MP Manns, H Wedemeyer, M Cornberg · Zeitschrift für Gastroenterologie · 2015 · Heft 01
Bibliografische Angaben
Zusammenfassung
Introduction: Hepatitis B core-related antigen (HBcrAg) combines the antigenic reactivity of denatured HBeAg, HBcAg and the core-related protein p22cr. HBcrAg has been introduced as additional marker of HBV infection. High levels of HBcrAg were an independent risk factor for HCC in a large Japanese cohort, while low levels may indicate inactive carrier status. We here aimed to analyze HBcrAg levels during treatment with nucleos(t)ide analogues (NIC) in a European cohort. Methods: We included 57 patients with chronic Hepatitis B that were previously either untreated or treated ineffectively. All patients started…
