CareLit Fachartikel

Effect of LDL-apheresis on the soluble form of Activated Leukocyte Cell Adhesion Molecule (ALCAM)

A Sulaj, R von Bauer, S Kopf, M Brune, M Mendler, PP Nawroth, T Fleming · Diabetologie und Stoffwechsel · 2015 · Heft 04

Dokument
1175442
CareLit-ID
Jahr
2015
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Diabetologie und Stoffwechsel
Autor:innen
A Sulaj, R von Bauer, S Kopf, M Brune, M Mendler, PP Nawroth, T Fleming
Ausgabe
Heft 04 / 2015
Seiten
–
Erschienen: 2015-04-29 00:00:00
ISSN
1861-9002

Zusammenfassung

Introduction/Background: Cardiovascular disease is the major cause of death in patients with diabetes and atherosclerosis is exacerbated under diabetes. Atherosclerosis is an inflammatory disorder in which several converging immune responses induce lipid accumulation in macrophages. Activated leukocyte cell adhesion molecule (ALCAM) functions as a pattern recognition receptor and its soluble form sALCAM is involved in ALCAM-dependent and -independent immune mechanisms. The aim of this study was to investigate the role of aggressive removal of low density lipoprotein-cholesterol (LDL-C) and lipoprotein(a) (Lp [a]…

Schlagworte

Atherosclerosis ALCAM After Activated-Leukocyte Cell Adhesion Molecule Cholesterol Apheresis Association Blood Diet Diabetologie und Stoffwechsel