High prevalence of Vitamin D deficiency in patients with autoimmune Hepatitis: impact on clinical presentation and response to treatment
S Beinhardt, M Eder, R Marculescu, R Strassl, A Stättermayer, J Stift, K Kozbial, C Freissmuth · Zeitschrift für Gastroenterologie · 2015 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background & Aims: Besides its role in calcium-homeostasis, vitamin D has shown to exert pleiotropic actions in patients with liver disease including immune-modulatory properties, which are of particular interest in autoimmune hepatitis (AIH). We analyzed the presence of vitamin D-deficiency and its association with laboratory, histological and clinical presentation in patients with AIH, as well as the response to immuno-suppressive treatment. Patients & Methods: Ninety six consecutive AIH-patients (m/f: 30/66; age: 40.9 ± 18.4 years[8 – 76]; mean ± SD [range]; AIH type-1 (N = 80/83.3%)) were retrospectively ana…
