Serum bile acids in cirrhosis depend on aetiology
A Horvath, B Leber, E Krones, G Zollner, P Fickert, RE Stauber, S Lemesch, W Spindelboeck, F Durchschein, P Douschan, P Stiegler, T Stojakovic, G Fauler, V Stadlbauer · Zeitschrift für Gastroenterologie · 2015 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background: Elevated serum bile acid levels are suggested to be a diagnostic tool as well as a predictor for mortality. After synthesis in the liver, and metabolization by intestinal microflora, bile acids are re-internalized. Characteristic liver damage, changes in microbiome and gut barrier dysfunction are likely to influence bile acid profilesaetiology-dependent. Therefore, we examined changes in bile acid profiles typical for different aetiologies of cirrhosis. Methods: Bile acid profiles of 101 cirrhotic patients (56 alcoholic, 20 chronic hepatitis C, 25 others) and 10 healthy controls were determined with…
