Hot Topics in Life Sciences: Genetic Variability, Pain and Disability
J Gjerstad · Physikalische Medizin Rehabilitationsmedizin Kurortmedizin · 2015 · Heft 06
Bibliografische Angaben
Zusammenfassung
Most pain states are temporary, i.e. the pain intensity is reduced along with the healing process. For some patients, however, pain persists and may become chronic. Such persistent pain conditions are often associated with a prolonged inflammatory process, which in turn may be related to functional cellular changes in the pain pathways. Earlier studies show that tissue damage associated with long-lasting inflammation enhances the neuronal activity in the sensory system. For example previous findings show that intervertebral disc herniation, and subsequent leakage of nucleus pulposus (NP) out of the disc, increas…