Improvement of liver function parameters in advanced HCV-associated liver cirrhosis by IFN-free antiviral therapies
K Deterding, C Höner zu Siederdissen, K Port, L Sollik, J Kirschner, C Mix, J Cornberg, H Mix, M Manns, M Cornberg, H Wedemeyer · Zeitschrift für Gastroenterologie · 2015 · Heft 08
Bibliografische Angaben
Zusammenfassung
Successful antiviral treatment of decompensated hepatitis B with HBV polymerase inhibitors is associated with improvement of liver function and even de-listing of patients on the transplant waiting list. To what extent liver function also improves in cirrhotic patients with chronic hepatitis C receiving novel IFN-free therapies is unknown. We here analysed 80 consecutive patients with advanced HCV associated liver cirrhosis including 34 patients (43%) with Child B/C cirrhosis and 42 patients (53%) with platelet counts of We show that (i) liver function parameters recover in the majority of patients when HCV repl…
