Effects of a temporal segmentation of meal composition on lipid and glucose metabolism in men
K Kessler, S Hornemann, KJ Petzke, M Kemper, N Rudovich, A Kramer, AFH Pfeiffer, O Pivovarova · Diabetologie und Stoffwechsel · 2016 · Heft 04
Bibliografische Angaben
Zusammenfassung
Background: In mice, strong metabolic consequences of a temporal segmentation of carbohydrate and fat consumption have been demonstrated with tremendous effects on blood glucose levels, beta-oxidation and body weight – features deteriorated in diabetics. Whether the same effects are seen in humans is not clear yet. We therefore aimed to investigate the effect of two different patterns of meal composition on substrate oxidation, lipid and glucose metabolism in men. Materials: In a cross-over study, 29 men (age 45.7 ± 2.5 years, BMI 27.1 ± 0.8 kg/m2) consumed isocaloric carbohydrate-rich meals in the morning and f…