Concordance of immunohistochemistry in core needle biopsy and surgical specimen in invasive breast cancer

Introduction: Immunohistochemical (IHC) evaluation on core needle biopsy is essential to guide further treatment. The aim of our study was to determine the concordance of histology and IHC in CNB and SS in patients with invasive breast cancer (BC). Material and methods: Retrospective analysis of data from patients with primary diagnosed BC at the university hospital of Berne between 2013 and 2015. Results: A total of 84 patients with a mean age of 60.3 years (32 – 91) were eligible for this study. Concordance analysis of receptor status revealed very good concordance for ER and PR expression; observed agreement…